6533b7d6fe1ef96bd12670c6

RESEARCH PRODUCT

Exploiting a list of protein sequences

Michael C. MardenDjemel HamdaneThorsten BurmesterThomas HankelnHenri WajcmanLaurent KigerLuc MoensVã©ronique Baudin-creuzaSylvia DewildeJulien UzanChantal Celier

subject

Models MolecularTheoretical computer scienceExploitProtein ConformationBiologyHemoglobinsSoftwareNeed to knowComputer GraphicsGeneticsAnimalsHumansAmino Acid SequenceAmino AcidsDatabases ProteinRepresentation (mathematics)BiologyGeneticsSequencebusiness.industryGeneral MedicineProtein Structure TertiaryMutationHuman medicinebusinessSoftware

description

Abstract: We describe a software program to help exploit a database of aligned protein sequences. In addition to the classical lists of sequences, a graphical representation is used to get a better overview of the information. As natural parameters, the type of amino acid and sequence position are used. Various plots or 3D representations are then updated. Examples are shown based on globin sequences from various species and on the abnormal human hemoglobins. The software should be of interest to protein engineers who need to know what variants are already known.

yearjournalcountryeditionlanguage
2007-08-01Gene
10.1016/j.gene.2007.01.036https://hdl.handle.net/10067/748210151162165141