6533b7d6fe1ef96bd1267156

RESEARCH PRODUCT

Dying with or because of invasive fungal infection? The role of immunity exhaustion on patient outcome

Andrea CortegianiVincenzo RussottoAntonino GiarratanoCesare GregorettiSanti Maurizio Raineri

subject

0301 basic medicineAntifungalmedicine.medical_specialtyEmergency Medicine; Anesthesiology and Pain Medicinebusiness.industrymedicine.drug_class030106 microbiology030208 emergency & critical care medicinemedicine.diseasesepsis fungal infectionOutcome (game theory)03 medical and health sciences0302 clinical medicineAnesthesiology and Pain MedicineAcquired immunodeficiency syndrome (AIDS)ImmunityAntifungal Treatment CORTEGIANI vs. DE ROSA: DEBATE Second RoundEmergency MedicineMedicineMED/41 - ANESTESIOLOGIAbusinessIntensive care medicine

description

De Rosa et al. considered clinical scores, biomarkers and their combination as useful aids for an early antifungal treatment and advocated the adoption of de-escalation therapy in an antifungal stewardship approach as a possible key for a better management of these patients. Authors considered the high burden of invasive fungal infections in terms of patient outcomes and costs and focused on current strategies for their optimization.

10.5152/tjar.2016.0013http://hdl.handle.net/10447/273006