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RESEARCH PRODUCT
Gas-liquid chromatography as a tool for evaluation of lipophilicity of selected esters of aromatic and aliphatic acids
V. RejholecMiroslav KuchařIlpo O.o. KorhonenH. Tomkovásubject
Partition coefficientChromatographyChemistryCapillary actionOrganic ChemistryLipophilicityOrganic chemistryGeneral MedicineGas chromatographyBiochemistryAnalytical Chemistrydescription
Abstract The use of gas-liquid chromatographic retention values for the determination of lipophilicity was studied for series of esters of aromatic and aliphatic acids and for series of aliphatic alcohols. The regression relationships between the logarithms of the partition coefficients and the retention characteristics measured on two capillary columns, SE-30 and OV-351, differing markedly in polarity, were evaluated. It may be deduced that, for the structurally similar compounds, the stationary phases used simulate the reference partitioning system octanol-water.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1986-01-01 | Journal of Chromatography A |