6533b7d7fe1ef96bd12683d5
RESEARCH PRODUCT
ChemInform Abstract: New Electrophilic Reactions of 2,2′-Bisindolyls with Acid Chlorides and Carbodienophiles.
Ulf PindurY.-s. Kimsubject
AcylationIndole testchemistry.chemical_classificationchemistry.chemical_compoundchemistryElectrophileAnthranilic acidOrganic chemistryDehydrogenationGeneral MedicineAldehydeArynedescription
Some new acylation and cyclization reactions of 2,2′-bisindolyls 1, 2 are described. The product patterns constitute acyl derivatives 3, 4, 5 and an aldehyde 7, indolo[2,3-a]carbazoles 6, 14, 17, 19, 20 and cyclopentadiindoles 22 and 24. In the reaction with aryne or diazotated anthranilic acid, a 3-benzoylindole derivative 9 and phenylindolyl azo dye 10 are formed. N-methylmaleimide reacts with 2,2′-bisindolyl 2 via Michael type addition, dehydrogenation and cyclization to several functionalized or anellated indole derivatives 11, 12, 13 and 14, respectively.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-08-04 | ChemInform |