6533b7d7fe1ef96bd1268d2a
RESEARCH PRODUCT
Bacterial Bioconversion of Primary Aliphatic and Aromatic Alcohols into Acids: Effects of Molecular Structure and Physico-chemical Conditions
Jean-marc BelinAnne EndrizziDominique DruauxGeorges Mangeotsubject
biologyRenewable Energy Sustainability and the EnvironmentBioconversionGeneral Chemical EngineeringButanolOrganic ChemistryAlcoholPrimary alcoholbiology.organism_classificationPollutionInorganic ChemistryButyric acidchemistry.chemical_compoundFuel TechnologychemistryBiotransformationOrganic chemistryAcetobacterWaste Management and DisposalBiotechnologyAcetobacter acetidescription
The biotransformation of four alcohol substrates (butanol, 2-methylbutanol, 3-methylbutanol and 2-phenylethanol) into their acids was studied using a strain of Acetobacter aceti. Bioconversion yields depended on the molecular structure of the alcohol. Biotransformation of high concentrations of alcohols was possible until the precursor reached an inhibiting concentration (3.8 g dm -3 for butanol and 3-methylbutanol, 4.2 g dm -3 for 2-methylbutanol). In contrast, biotransformation of 2-phenylethanol decreased when alcohol concentration was higher than 0.3 g dm -3 . Dissolved oxygen concentrations and pH conditions of the medium were important factors in improving bioconversion. Transformation of 2-methylbutanol into the corresponding acid was increased when dissolved oxygen partial pressure increased from 60 to 80% and regulation at pH 6 allowed an increase in the production of butyric acid from butanol.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-02-01 | Journal of Chemical Technology & Biotechnology |