6533b7d7fe1ef96bd1268dbc

RESEARCH PRODUCT

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subject

Genetically modified mouseHepatitis B virusRegulation of gene expressionMultidisciplinaryTransgenevirus diseasesHepatitis BBiologymedicine.disease_causemedicine.diseasedigestive system diseasesFibrosisImmunologySTAT proteinmedicineSignal transduction

description

Background While the immune pathogenesis caused by hepatitis B virus (HBV) infection has been studied extensively, little is known about direct pathogenic effects of HBV surface proteins. Here, we have investigated pathological cellular effects of HBV surface protein expression in the liver of transgenic mice with different genetic background.