6533b7d8fe1ef96bd1269748

RESEARCH PRODUCT

ChemInform Abstract: Dual Hydrogen-Bond/Enamine Catalysis Enables a Direct Enantioselective Three-Component Domino Reaction.

ÁDám MadarászHasibur RahamanImre PápaiPetri M. Pihko

subject

chemistry.chemical_compoundCascade reactionHydrogen bondComponent (thermodynamics)ChemistryOrganocatalysisEnantioselective synthesisGeneral MedicineCombinatorial chemistryCatalysisDual (category theory)Enamine

description

A dual system, composed of an enantioselective enamine catalyst and a multiple-hydrogen-bond catalyst achieves the three-component enantioselective aldehyde—nitroalkene—aldehyde domino reaction using either two similar or two different aldehydes.

https://doi.org/10.1002/chin.201142043