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RESEARCH PRODUCT

AB1390 Osteoporosis associated morbidity analysis can reveal targets for better disease diagnosis and management

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Background Osteoporosis accounts for more disability and life years lost than rheumatoid arthritis. It brings an elevated risk of mortality, morbidity and re-/hospitalisation due to fractures and a significant financial and social burden. A rationale use of diagnostic and therapeutic resources is useful and should be encouraged at all intervention levels. For admitted patients, clinical risk factors for fractures and conditions that are causes for secondary osteoporosis should trigger either the diagnosis approach or the referral to a (Rheumatology/Endocrinology) specialist and treatment should be started during hospitalisation. Objectives We aimed to identify targets for educational or protocol interventions in order to improve inpatient osteoporosis diagnosis and subsequent management. Methods A retrospective three years (2014–2016) cross-sectional prevalence analysis of comorbidities in all hospitalised patients with osteoporosis in our general hospital was conducted. We used the medical records database of our hospital. Results Osteoporosis as a principal diagnosis was found in 46 cases, mostly from the Endocrinology Department (65%). Osteoporosis as a secondary diagnosis was found in 2464 cases, and only 11% were diagnose-associated with fractures. 23% of all comorbidities are of endocrine or diabetic etiology. A small percent of osteoporosis cases have simultaneous skeletal disease, mostly vertebral fractures, osteomalacia or degenerative disease. Only 8,77% of secondary osteoporosis was diagnosed in the Orthopaedic Department. No osteoporosis was mentioned in association with COPD or oncologic disease. Only 65% of patients leaving the hospital had specific recommendation for anti-osteoporotic medication. Conclusions Osteoporosis should be mentioned in all cases in the patients medical records that are further sent to the general practitioner. Osteoporosis may be better diagnosed in diabetic, oncologic, COPD, Parkinson disease patients and in a large percent of fracture patients if internal referral protocols will be implemented. Appropriate therapy should be recommended from the hospital specialists. References [1] Vranken L et all. The Phenotype of Patients with a Recent Fracture: A Literature Survey of the Fracture Liaison Service. Calcif Tissue Int (2017)101:248–258 [2] Briggs AM et all. Hospitalisations, admission costs and re-fracture risk related to osteoporosis in Western Australia are substantial: a 10-year review. Aust N Z J Public Health. 2015Dec;39(6):557–62. [3] Svedbom A et all. Epidemiology and economic burden of osteoporosis in Switzerland. Arch Osteoporos. 2014;9:187. [4] Kanis J.A. European Guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis Int (2013) 24, 23–57. Disclosure of Interest None declared