6533b7d8fe1ef96bd12698d2
RESEARCH PRODUCT
Understanding the affinity of bis-exTTF macrocyclic receptors towards fullerene recognition
Nazario MartínNazario MartínJoaquín CalboEmilio M. PérezJuan AragóEnrique OrtíJulia VillalvaAlberto De Juansubject
chemistry.chemical_classificationFullereneGeneral Physics and Astronomy02 engineering and technologySynergistic combination010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences3. Good health0104 chemical sciencesAlkyl etherchemistry.chemical_compoundCrystallographychemistryChlorobenzeneNon-covalent interactionsPhysical and Theoretical Chemistry0210 nano-technologyReceptordescription
A new series of fullerene receptors based on exTTF macrocycles with alkyl ether chains of increasing length is reported. The novel macrocyclic receptors are able to favourably interact with fullerene C60 through a synergistic combination of π–π, CH⋯π and n⋯π noncovalent interactions. We identify that the highest affinity towards C60 recognition is achieved for the host with the tightest fit; that is, the smallest receptor with a cavity large enough to host the buckyball inside (log Ka = 5.2 in chlorobenzene at 298 K). However, besides this expected observation, theoretical calculations evidence that the most stable self-assembling configuration corresponds for all the receptors to an outside-ring binding mode, in which the C60 guest is out of the cavity of the receptor. The higher stability of this configuration results from the smaller deformation energy it implies for the receptor, and allows to explain the experimental trends in the association constants.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-05-28 | Physical Chemistry Chemical Physics |