Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia.

6533b7d8fe1ef96bd12699ed

RESEARCH PRODUCT

Adherence to antibiotic treatment guidelines and outcomes in the hospitalized elderly with different types of pneumonia.

R Rossio C Franchi I Ardoino Cd Djade M Tettamanti L Pasina F Salerno A Marengoni S Corrao M Marcucci F Peyvandi Em Biganzoli A Nobili Pm Mannucci M Mannucci A Nobili M Tettamanti L Pasina C Franchi F Salerno S Corrao A Marengoni M Marcucci E Sparacio S Alborghetti R Di Costanzo Tk Eldin M Tettamanti Cd Djade D Prisco E Silvestri C Cenci T Barnini G Delitala S Carta S Atzori G Guarnieri M Zanetti A Spalluti Mg Serra Ma Bleve M Vanoli G Grignani G Casella L Gasbarrone G Maniscalco M Gunelli D Tirotta A Brucato S Ghidoni P Di Corato M Bernardi S Li Bassi L Santi G Agnelli A Iorio M Marcucci E Marchesini E Mannarino G Lupattelli P Rondelli F Paciullo F Fabris M Carlon F Turatto Mc Baroni M Zardo R Manfredini C Molino M Pala F Fabbian R Nuti R Valenti M Ruvio S Cappelli G Paolisso Mr Rizzo Mt Laieta T Salvatore Fc Sasso R Utili E Durante Mangoni D Pinto O Olivieri Am Stanzial R Fellin S Volpato S Fotini M Barbagallo L Dominguez L Plances D D'angelo G Rini P Mansueto I Pepe G Licata L Calvo M Valenti C Borghi E Strocchi Er Rinaldi M Zoli E Fabbri D Magalotti A Auteri Al Pasqui L Puccetti F Laghi Pasini Pl Capecchi M Bicchi C Sabbà Fs Vella A Marseglia Cv Luglio G Palasciano Me Modeo A Aquilino S Pugliese C Capobianco A Postiglione Mr Barbella F De Stefano L Fenoglio C Brignone C Bracco A Giraudo G Musca O Cuccurullo L Cricco A Fiorentini Md Cappellini G Fabio S Seghezzi Mm De Amicis S Fargion P Bonara M Bulgheroni R Lombardi F Magrini F Massari T Tonella F Peyvandi A Tedeschi R Rossio G Moreo B Ferrari L Roncari V Monzani V Savojardo C Folli M Magnini D Mari Pd Rossi S Damanti S Prolo Ms Lilleri L Cricco A Fiorentini G Micale M Podda C Selmi F Meda F Salerno S Accordino A Conca V Monti Gr Corazza E Miceli Mv Lenti D Padula Cl Balduini G Bertolino S Provini F Quaglia G Murialdo M Bovio F Dallegri L Ottonello A Quercioli A Barreca Mb Secchi D Ghelfi Ws Chin L Carassale S Caporotundo L Anastasio L Sofia M Carbone S Di Carlo G Traisci L De Feudis G Davì Mt Guagnano S Sestili E Bergami E Rizzioli C Cagnoni L Bertone A Manucra A Buratti T Tognin Nl Liberato G Bernasconi B Nardo Gb Bianchi S Giaquinto G Benetti M Quagliolo Gr Centenaro F Purrello A Di Pino S Piro G Mancuso D Calipari M Bartone F Gullo M Cortellaro M Magenta F Perego Mr Meroni M Cicardi A Gidaro M Magenta A Sacco A Bonelli G Dentamaro R Rozzini L Falanga A Giordano Pc Perin B Lorenzati G Gruden G Bruno G Montrucchio E Greco P Tizzani G Fera Ml Di Luca D Renna A Perciccante A Coralli R Tassara D Melis L Rebella G Menardo S Bottone E Sferrazzo C Ferri R Striuli R Scipioni R Salmi P Gaudenzi S Gamberini F Ricci C Morabito R Fava A Semplicini L Gottardo G Delitala S Carta S Atzori G Vendemiale G Serviddio R Forlano L Bolondi L Rasciti I Serio C Masala A Mammarella V Raparelli F Rossi Fanelli M Delfino A Amoroso F Violi S Basili L Perri P Serra V Fontana M Falcone R Landolfi A Grieco A Gallo G Zuccalà F Franceschi G De Marco C Chiara S Marta M Bellusci D Setti F Pedrazzoli G Romanelli C Pirali C Amolini Ea Rosei D Rizzoni L Castoldi A Picardi Uv Gentilucci C Mazzarelli P Gallo Luigina Guasti Luana Castiglioni Andrea Maria Maresca Alessandro Squizzato Sara Contini Marta Molaro G Annoni M Corsi S Zazzetta M Bertolotti C Mussi R Scotto Ma Ferri F Veltri F Arturi E Succurro G Sesti U Gualtieri F Perticone A Sciacqua M Quero C Bagnato P Loria Ma Becchi G Martucci A Fantuzzi M Maurantonio R Corinaldesi R De Giorgio M Serra V Grasso E Ruggeri Lm Carozza F. Pignatti

subject

Male Antibiotic regimen Guidelines adherence Settore MED/09 - Medicina Interna Antibiotics Logistic regression Elderly Community-acquired pneumonia Antibiotics 80 and over Elderly people Age Factor Hospital Mortality Aged 80 and over Treatment regimen Medicine (all)Age Factors Optimal management Antibiotics; Elderly; Guidelines adherence; Mortality; Pneumonia; Re-hospitalization; Age Factors; Aged; Aged 80 and over; Anti-Bacterial Agents; Female; Hospital Mortality; Humans; Logistic Models; Male; Pneumonia; Practice Guidelines as Topic; Treatment Outcome; Guideline Adherence; Hospitalization; Internal Medicine; Medicine (all)Anti-Bacterial Agents Hospitalization Treatment Outcome Practice Guidelines as Topic Female Guideline Adherence Human medicine.medical_specialty Logistic Model medicine.drug_class Socio-culturale antibiotic treatment; guidelines; pneumonia; elderly;Internal medicine Re-hospitalization Anti-Bacterial Agent medicine Internal Medicine Humans elderly pmeumonia antibiotics guidelines adherence mortality re-hospitalization pmeumonia Mortality Intensive care medicine Antibiotics; Elderly; Guidelines adherence; Mortality; Pneumonia; Re-hospitalization; Age Factors; Aged; Aged 80 and over; Anti-Bacterial Agents; Female; Hospital Mortality; Humans; Logistic Models; Male; Pneumonia; Practice Guidelines as Topic; Treatment Outcome; Guideline Adherence; Hospitalization; Internal Medicine Aged business.industry Settore MED/09 - MEDICINA INTERNA Antibiotic Pneumonia medicine.disease Pneumonia Antibiotics; Elderly; Guidelines adherence; Mortality; Pneumonia; Re-hospitalization Logistic Models Antibiotics; Elderly; Guidelines adherence; Mortality; Pneumonia; Re-hospitalization; Age Factors; Aged; Aged 80 and over; Anti-Bacterial Agents; Female; Hospital Mortality; Humans; Logistic Models; Male; Pneumonia; Practice Guidelines as Topic; Treatment Outcome; Guideline Adherence; Hospitalization business

description

none 22 no Background: Few studies evaluated the clinical outcomes of Community Acquired Pneumonia (CAP), Hospital-Acquired Pneumonia (HAP) and Health Care-Associated Pneumonia (HCAP) in relation to the adherence of antibiotic treatment to the guidelines of the Infectious Diseases Society of America (IDSA) and the American Thoracic Society (ATS) in hospitalized elderly people (65 years or older). Methods: Data were obtained from REPOSI, a prospective registry held in 87 Italian internal medicine and geriatric wards. Patients with a diagnosis of pneumonia (ICD-9 480-487) or prescribed with an antibiotic for pneumonia as indication were selected. The empirical antibiotic regimen was defined to be adherent to guidelines if concordant with the treatment regimens recommended by IDSA/ATS for CAP, HAP, and HCAP. Outcomes were assessed by logistic regression models. Results: A diagnosis of pneumonia was made in 317 patients. Only 38.8% of them received an empirical antibiotic regimen that was adherent to guidelines. However, no significant association was found between adherence to guidelines and outcomes. Having HAP, older age, and higher CIRS severity index were the main factors associated with in-hospital mortality. Conclusions: The adherence to antibiotic treatment guidelines was poor, particularly for HAP and HCAP, suggesting the need for more adherence to the optimal management of antibiotics in the elderly with pneumonia. none Raffaella Rossio; Carlotta Franchi; Ilaria Ardoino; Codjo D. Djade; Mauro Tettamanti; Luca Pasina; Francesco Salerno; Alessandra Marengoni; Salvatore Corrao; Maura Marcucci; Flora Peyvandi; Elia M. Biganzoli; Alessandro Nobili; Pier Mannuccio Mannucci; REPOSI Investigators [...; Mauro Bernardi; Claudio Borghi; Marco Zoli; Luigi Bolondi; Roberto Corinaldesi; Roberto De Giorgio;...] Raffaella Rossio; Carlotta Franchi; Ilaria Ardoino; Codjo D. Djade; Mauro Tettamanti; Luca Pasina; Francesco Salerno; Alessandra Marengoni; Salvatore Corrao; Maura Marcucci; Flora Peyvandi; Elia M. Biganzoli; Alessandro Nobili; Pier Mannuccio Mannucci; REPOSI Investigators [..; Mauro Bernardi; Claudio Borghi; Marco Zoli; Luigi Bolondi; Roberto Corinaldesi; Roberto De Giorgio;..]

year	journal	country	edition	language
2015-01-01

http://hdl.handle.net/10447/144592