6533b7d8fe1ef96bd1269a01

RESEARCH PRODUCT

Aspects of excessive antibiotic consumption and environmental influences correlated with the occurrence of resistance to antimicrobial agents

Lotfi AleyaDana Carmen ZahaSimona BungauDelia Mirela TitTapan Behl

subject

medicine.medical_specialtyAntibiotic resistancemedicine.drug_classHealth Toxicology and Mutagenesis0208 environmental biotechnologyAntibiotics02 engineering and technology010501 environmental sciencesBiologyExcessive antibiotic consumption01 natural sciencesAntibiotic resistanceEnvironmental factorsmedicineEnvironmental ChemistryEcosystem0105 earth and related environmental sciences2. Zero hungerResistance (ecology)business.industryPublic healthPublic Health Environmental and Occupational HealthInternational healthContaminationAntimicrobial6. Clean water020801 environmental engineering3. Good healthBiotechnologyHealth13. Climate action[SDE]Environmental Sciencesbusiness

description

International audience; This article explores the correlation between specific aspects of antibiotic usage, their resistance development, and environmental factors. The indiscriminate use of antibiotics led to environment contamination, selection and spreading of antibiotic-resistant organisms, and alteration of the microbial ecosystems balance. Sociobehavioural environmental factors and changes in the natural environment are major contributors to resistance development. Resistant bacteria strains' isolation in food, water, soil etc. demonstrates the environmental influence on the strains through antibiotics accumulation in the environment. It is difficult to assess the impact of antibiotic consumption on public health and the environment. Reducing irrational consumption, restoring microbial ecosystems, adopting methodologies to control antimicrobial resistance in case of in-hospital infections, implementation of measures included in national/international health policies are the main solutions for this problem.

https://doi.org/10.1016/j.coesh.2020.10.012