6533b7d8fe1ef96bd1269b23

RESEARCH PRODUCT

Successful Topical Application of Caspofungin in the Treatment of Fungal Keratitis Refractory to Voriconazole

Javier Peman-garcíiaManuel Díiaz-llopisAmparo Vazquez-poloAngel Cisneros-lanuzaAntonio M. Duch-samperMercedes Hurtado-sarrió

subject

Voriconazolemedicine.medical_specialtybusiness.industryEye diseaseFongs patògensmedicine.diseasecorneal ulcerCaspofungin AcetateKeratitisSurgeryOphthalmologychemistry.chemical_compoundRefractorychemistrymedicineFungal keratitisCaspofunginbusinessmedicine.drug

description

Fungal keratitis is an important ophthalmic problem because it leads to corneal blindness and sometimes to loss of the eye.1,2 There is no agreed protocol for the treatment of suspected fungal keratitis. Topical and oral voriconazole have now been reported to be effective.3 However, some cases do not respond to this treatment. New antifungal agents such as caspofungin acetate, 0.5%, are promising alternatives

yearjournalcountryeditionlanguage
2010-07-01Archives of Ophthalmology
https://doi.org/10.1001/archophthalmol.2010.110