6533b7d8fe1ef96bd1269b3f

RESEARCH PRODUCT

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Beate St PourcainAbhishek NagFederico MurgiaEmily Y. ChewVeluchamy A. BarathiVeluchamy A. BarathiJames F. WilsonJamie E CraigVeronique VitartMyopia (Cream)Olavi PärssinenCathy WilliamsSarayut JanmahasatianAlex W. HewittAlex W. HewittFelicia HawthorneNorbert PfeifferYik Ying TeoJohannes R. VingerlingShea Ping YipAlan F. WrightTanja ZellerRobert P. IgoDavid M. EvansMaria SchacheNicholas J. TimpsonFernando RivadeneiraE-shyong TaiCraig E. PennellOzren PolasekOlli T. RaitakariTin AungTin AungChristian P. MüllerRené HöhnPaul MitchellLennart C. KarssenGeorge McmahonMika KähönenJuho WedenojaTien Yin WongTien Yin WongAngela DöringJost B. JonasAlbert HofmanKonrad OexleJugnoo S RahiJugnoo S RahiJugnoo S RahiComplications TrialBen A. OostraKathryn P. BurdonPirro G. HysiSudha K. IyengarTim D. SpectorLi Jia ChenClaire L. SimpsonS. Mohsen HosseiniDwight StambolianAlireza MirshahiArthur A.b. BergenTerri L. YoungRick Twee-hee OngAndres MetspaluIoana CotlarciucLiang XuXin ZhouToomas HallerVirginie J. M. VerhoevenDavid A. MackeyDavid A. MackeyBrian W FleckAndré G. UitterlindenJohn P. KempChi Pui PangSeang-mei SawSeang-mei SawSeang-mei SawThomas MeitingerGabriëlle H.s. BuitendijkPeng ChenJoan E. Bailey-wilsonJoan E. Bailey-wilsonWei AngStuart MacgregorCaroline HaywardAndrew D. PatersonJie Jin WangJie Jin WangRuoying LiCornelia M. Van DuijnChing-yu ChengChing-yu ChengJiemin LiaoTheo G. M. F. GorgelsAnnemieke J.m.h. VerkerkMario PirastuRobert WojciechowskiRobert WojciechowskiChristopher J HammondChristopher J HammondPaul N. BairdQiao FanGrant W. MontgomeryJeremy A. GuggenheimWan Ting TayM. Kamran IkramM. Kamran IkramTerho LehtimäkiEkaterina Yonova-doingNajaf AminRonald KleinKari-matti MäkeläChiea Chuen KhorChiea Chuen KhorBarbara E.k. KleinEranga N. VithanaYingfeng ZhengPhillippa M. CumberlandCaroline C W KlaverCaroline C W KlaverHoi Suen WongAniket MishraDaniel W.h. HoDaniel W.h. HoIgor RudanComplications (Dcct)Jonathan H. LassZoran Vatavuk

subject

Candidate geneRefractive errorBone Morphogenetic Protein 2Genome-wide association studyVARIANTSGenomeGenome-wide association studies0302 clinical medicineRisk FactorsMyopiaGRIA4Genetics0303 health sciencesKCNQ Potassium ChannelsDisease geneticsEYE GROWTHASSOCIATIONRETINAL-PIGMENT EPITHELIUMRefractive ErrorsGenetic load3. Good healthADAPTED MOUSE RETINAMeta-analysisACIDPOTASSIUM CHANNELEXPRESSIONSingle-nucleotide polymorphismBiologyWhite PeopleArticle03 medical and health sciencesAsian PeoplemedicineGeneticsHumansGenetic Predisposition to DiseaseReceptors AMPAgene; myopia; refractive030304 developmental biologyHomeodomain Proteinsta1184ta3121medicine.diseaseGENEAlcohol OxidoreductasesSERINE-PROTEASEbiology.protein030221 ophthalmology & optometrySusceptibility locusTrans-ActivatorsEye disorderLamininSerine ProteasesGWAS; meta-analyses; refractive error; myopiaGenome-Wide Association Study

description

Author version made available in accordance with the publisher's policy.

yearjournalcountryeditionlanguage
2013-02-10Nature Genetics
10.1038/ng.2554http://juuli.fi/Record/0252622013