6533b7d8fe1ef96bd126a1b9

RESEARCH PRODUCT

ATD perimetry in glaucoma and ocular hypertensive patients. A preliminar study

subject

description

Purpose: The new ATD perimetry assesses contrast sentivity thresholds for the three afferent sensory pathways of the visual system. Our aim is to compare contrast sensitivity to stimuli with different spatio-temporal frequencies in glaucomatous (G) and ocular hypertensive (OHT) subjects. Methods: Twenty three G and OHT subjects were selected from the ophthalmic clinic, all subjects signed an informed consent. Inclusion criteria were diagnosis of G or OHT, normal Farnsworth-Munsell color test, ametropia less than 6 D, visual acuity over 20/30, absence of previous ocular surgery and experience in perimetry. Twenty locations and the fovea were evaluated in a 60o x 40o fovea-centered field. Eight gabor stimuli were used: 0.5cpd-12Hz, 0.5cpd-24Hz, 4cpd-2Hz and 4cpd 12Hz, modulated along the achromatic (A) direction, 0.5cpd-12Hz and 4cpd-2Hz along the red/green (T) and blue/yellow (D) directions. Statistical analysis included ANOVA and Scheffe tests. Results: Mean thresholds for G and OHT were respectively, 0.4872 ± 0.5323 and 0.1077 ± 0.1922, for A 0.5cpd-12Hz; 0.7296 ± 0.5925 and 0.2280 ± 0.2246 for stimulus A 0.5cpd-24Hz; 1.4444 ± 0.5244 and 1,2671 ± 0.6138 for A 4cpd-2Hz; and 0.7751 ± 0.1937 and 0.6851 ± 0.2379 for D 0.5cpd-12Hz. Significant statistical differences (p<0.05) were found between G and OHT groups only with these stimuli. Conclusions: These preliminary results show that certain stimuli may differentiate between G and OHT subjects. A larger population sample, including glaucoma suspects, is currently under study.