6533b7d8fe1ef96bd126a2d6
RESEARCH PRODUCT
Phospholipid-based reverse micelles.
Peter WaldePier Luigi LuisiC. Andrea BoicelliAnna Maria Giulianisubject
chemistry.chemical_classificationfood.ingredientChemical PhenomenaOrganic Chemistrytechnology industry and agriculturePhospholipidBiological membraneCell BiologyBiochemistryMicelleLecithinColloidchemistry.chemical_compoundChemistryEnzymefoodchemistryPhosphatidylcholineOrganic chemistrylipids (amino acids peptides and proteins)MicroemulsionColloidsMolecular BiologyMicellesPhospholipidsdescription
Physicochemical investigations on the aggregation of phospholipids (mainly phosphatidylcholines) in organic solvents are reviewed and compared with the aggregation behaviour of phospholipids in aqueous medium. In particular we review the data showing that phosphatidylcholines (lecithins) form reverse micellar structures in certain apolar solvents. In these systems not only low molecular weight compounds but also catalytically active enzymes and entire cells can be solubilized. In addition, highly viscous phosphatidylcholine gels can be obtained in organic solvents upon solubilizing a critical amount of water. Generally, phospholipid-based reverse micelles can be regarded as thermodynamically stable models for inverted micellar lipid structures possibly occurring in biological membranes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-03-01 | Chemistry and physics of lipids |