6533b7d8fe1ef96bd126a597

RESEARCH PRODUCT

Imprinted chiral stationary phases in high-performance liquid chromatography

Börje Sellergren

subject

chemistry.chemical_classificationChromatographyManufacturing processChemistryOrganic ChemistryStereoisomerismGeneral MedicinePolymerBiochemistryHigh-performance liquid chromatographyAnalytical ChemistryTemplatePhase compositionEnantiomerMolecular imprintingChirality (chemistry)Chromatography High Pressure Liquid

description

Polymers imprinted with chiral templates offer a new generation of tailor-made chiral stationary phases (CSPs) with predictable selectivities. This review summarizes the present state of the art of molecular imprinting to generate tailor-made CSPs and provides an overview of the main factors involved in the manufacturing process that are crucial to the chromatographic performance of the phases.

https://doi.org/10.1016/s0021-9673(00)00929-8