6533b7d8fe1ef96bd126ae37
RESEARCH PRODUCT
A case-control study of amyotrophic lateral sclerosis
Brigida FierroGiuseppe SalemiMaria CassataAntonio ArcaraGiovanni SavettieriM G Castiglionesubject
Malemedicine.medical_specialtyEpidemiologybusiness.industryAmyotrophic Lateral SclerosisCase-control studyRetrospective cohort studyDiseaseOdds ratiomedicine.diseasePhysical medicine and rehabilitationItalyRisk FactorsCase-Control StudiesInternal medicinemedicineHumansFemaleSettore MED/26 - NeurologiaNeurology (clinical)First-degree relativesAmyotrophic lateral sclerosisbusinessRetrospective Studiesdescription
A retrospective case-control study was conducted using 46 patients affected by amyotrophic lateral sclerosis and 92 closely matched healthy controls. Cases were ascertained through typical clinical and instrumental findings. Putative risk factors (bone fractures or major trauma, exposure to domestic animals, surgical operations, disease among first degree relatives and others) were investigated anamnestically using a standard questionnaire. Using Mantel-Haenzsel estimates of the odds ratio, no association was found between amyotrophic lateral sclerosis and the investigated variables.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1991-01-01 |