6533b7d8fe1ef96bd126af39

RESEARCH PRODUCT

Immunologic diseases and brain tumors

Nuria AragonésTeresa Garcia-martinezMarina PollánMaría Morales-suárez-varelaRaquel Solis-plazaAgustín Llopis-gonzález

subject

AdultRiskPathologymedicine.medical_specialtyImmunologyMEDLINENegative associationBioinformaticsCohort StudiesImmunologic diseasesImmunology and AllergyMedicineAnimalsHumansChildPharmacologyClinical Trials as Topicbusiness.industryMechanism (biology)Brain NeoplasmsCase-control studyImmunityGeneral MedicineUnited StatesEuropeImmune System DiseasesCase-Control StudiesImmunological diseasesCentral nerve systembusinessCohort study

description

To do a bibliographic review of the given association of atopic [AD] and immunological diseases with central nerve system tumors [CNST] described a few years ago and to know the knowledge available. It gives an overview of the studies describing this association, and those explaining its mechanism. A negative association of AD with CNST stands out in case-control studies, which is not observed in cohort studies. The greatest association is seen for gliomas and is less significant for meningiomas. A clearer definition for the AD under study, tumour types, and the exact biochemical and clinical parameters to help diagnoses are the recommended as well as to establish an aetiologic and temporal relationship between AD and CNST.

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