6533b7d8fe1ef96bd126aff3

RESEARCH PRODUCT

Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst.

Ahlam SibaouihMarkku LeskeläTeemu NiemiAfnan Al-hunaitiTimo RepoPetri M. Pihko

subject

Primary (chemistry)Solvent free010405 organic chemistryChemistryMetals and AlloysGeneral ChemistryPrimary alcohol010402 general chemistry01 natural sciencesCatalysis0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsCatalysisThyminelaw.inventionchemistry.chemical_compoundMagazinelawAlcohol oxidationMaterials ChemistryCeramics and CompositesHigh activityOrganic chemistry

description

In this study, we developed an efficient and selective iron-based catalyst system for the synthesis of ketones from secondary alcohols and carboxylic acids from primary alcohol. In situ generated iron catalyst of thymine-1-acetate (THA) and FeCl(3) under solvent-free condition exhibits high activity. As an example, 1-octanol and 2-octanol were oxidized to 1-octanoic acid and 2-octanone with 89% and 98% yields respectively.

10.1039/c0cc04043fhttps://pubmed.ncbi.nlm.nih.gov/21042629