6533b7d8fe1ef96bd126b6ee

RESEARCH PRODUCT

Effects of nicotinamide adenine dinucleotide hydride on physical and mental performance

Riikka RaitanenPaavo V. KomiAntti A. MeroJoerg Birkmayer

subject

Malemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationNicotinamide adenine dinucleotidePlaceboPlaceboschemistry.chemical_compoundCognitionOxygen ConsumptionDouble-Blind MethodInternal medicinemedicineHumansOrthopedics and Sports MedicineLactic AcidCreatine KinaseCross-Over StudiesNicotinamidebiologyHydrideVO2 maxNADB vitaminsEndocrinologyBiochemistrychemistryAustriaExercise Testbiology.proteinCreatine kinaseAnaerobic exercise

description

The aim of this study was to assess the effects of nicotinamide adenine dinucleotide hydride (NADH) on maximal oxygen uptake (VO2max), maximal anaerobic running time, and mental performance. Eight men were exposed to a supplement treatment (30 mg NADH as ENACHI tablets per day) and to a placebo treatment, each of 4 weeks' duration, in a balanced, double-blind, and cross-over design. The two treatments were separated by a 14-week wash-out period. The results indicated that VO2max, maximal anaerobic running time, and the ability to concentrate were similar in the NADH and placebo conditions. There were also no differences in blood lactate, creatine kinase, reaction time or feelings of fatigue between the treatments. A counter-movement jump performed at rest and 2 min after the aerobic test differed significantly (Por= 0.05) between the treatment conditions and was higher in the NADH group. In conclusion, the NADH supplementation for 4 weeks had no effects on VO2max, maximal anaerobic running time or mental performance.

https://doi.org/10.1080/02640410701474200