6533b7d8fe1ef96bd126b87f

RESEARCH PRODUCT

Acetogenins, Aporphinoids, and Azaanthraquinone from Annona cherimolia Seeds.

Serafin ValverdeJosé Luis RíosDiego Cortes

subject

Pharmacologychemistry.chemical_classificationFolk medicinebiologyStereochemistryAlkaloidOrganic ChemistryPharmaceutical ScienceGlycosideCleistopholinebiology.organism_classificationAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryAnnonaceaeDrug DiscoveryAcetogeninMolecular MedicineIsoquinolineAnnona cherimolia

description

We have isolated several known steroids, glycosides, isoquinoline, and azaanthraquinone alkaloids, and five acetogenins belonging to a new group of secondary metabolites, the bis-tetrahydrofuran gamma-lactones, from the seeds of ANNONA CHERIMOLIA. The azaanthraquinone alkaloid isolated was identified as cleistopholine. One new acetogenin is reported here: laherradurine; a second new one was isolated, but its structure has not been determined. The other three: cherimoline, dihydrocherimoline, and asimicine have already been reported.

10.1055/s-2006-962020https://pubmed.ncbi.nlm.nih.gov/17262431