6533b7d9fe1ef96bd126ba4d

RESEARCH PRODUCT

Binding abilities of new cyclodextrin-cucurbituril supramolecular hosts

RielaS. Arcudi FG. LazzaraL. MeoP. GuernelliS. D'annaF. MiliotoN. S

subject

chemistry.chemical_classificationcucubiturilCyclodextrinsmedicine.diagnostic_testCyclodextrinHydrochloridecucurbiturilsSupramolecular chemistryIsothermal titration calorimetryGeneral ChemistrySettore CHIM/06 - Chimica OrganicaMass spectrometrycucurbiturilThermogravimetryCrystallographychemistry.chemical_compoundcyclodextrinchemistryComputational chemistryCucurbiturilSpectrophotometrymedicinecucurbiturils; Cyclodextrins; supramolecular co-polymerssupramolecular co-polymerscyclodextrins; cucurbiturils; supramolecular co-polymers

description

Various combined techniques (UV–vis spectrophotometry, isothermal titration calorimetry, thermogravimetry, ESI-MS mass spectrometry, polarimetry and 1H NMR spectroscopy) were used in order to study the interaction between a new combined supramolecular host, namely a bow-tie-structured cyclodextrin–cucurbituril association solely held by non-covalent interactions, and a suitably selected guest, namely the N-(p-nitrophenyl)-1,8-diaminooctane hydrochloride. In particular, the use of different techniques highlighted the peculiar features of the possible host–guest supramolecular interactions under different concentration conditions.

yearjournalcountryeditionlanguage
2015-01-01
10.1080/10610278.2014.975704https://hdl.handle.net/11577/3473969