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RESEARCH PRODUCT
Ossified spinal meningiomas: Clinical and surgical features
Francesco M. SalpietroFrancesco TomaselloConcetta AlafaciGiovanni GrassoFrancesca Granatasubject
AdultMalemedicine.medical_specialtyUrinary incontinenceNeurosurgical ProceduresLesionMeningioma03 medical and health sciences0302 clinical medicineGross total resectionmedicineMeningeal NeoplasmsHumansMeningeal NeoplasmAgedRetrospective StudiesMetaplastic meningiomaAged 80 and overbusiness.industrySettore MED/27 - NeurochirurgiaRetrospective cohort studyGeneral MedicineHypoesthesiaMetaplastic MeningiomaMiddle Agedmedicine.diseaseSpinal cordSurgerymedicine.anatomical_structureTreatment OutcomeGross total resection; Metaplastic meningioma; Ossified spinal tumor030220 oncology & carcinogenesisSurgeryFemaleNeurology (clinical)Ossified spinal tumormedicine.symptomNeoplasm Recurrence LocalbusinessMeningioma030217 neurology & neurosurgerydescription
Abstract Object Meningiomas constitute 25% of primary spinal tumors and predominantly involve the thoracic spinal cord. Although calcifications are commonly seen in intracranial meningiomas, gross calcifications are observed in only 1–5% of all spinal meningiomas. We report the clinical findings, surgical strategy and histological features of 9 patients with ossified spinal meningiomas (OSMs). Patients and methods Clinical and surgical features of 9 patients with ossified spinal meningiomas were retrospectively reviewed. Results There were 8 women and 1 man with a mean age of 59 years. In 7 patients, the lesions were localized in the thoracic segment of the spine while in 2 patients in the lower cervical segment. All patients presented with weakness of the lower limbs and hypoesthesia below the site level of the lesion. Only 2 patients presented with urinary incontinence. Gross-total resection of the tumor was achieved in 6 patients while in 3 a subtotal removal of the meningioma was obtained. In all patients the postoperative course was uneventful. Six patients presented with a significant neurological improvement while in 3 patients a mild improvement was observed. Microscopically, all tumors showed typical histological pattern of ossified meningioma. Conclusions OSMs are amenable to surgery if the complete removal can be achieved. Because of their hard-rock consistency complete resection can be challenging. In difficult cases, subtotal removal can be advised and follow-up imaging is mandatory. Overall, the risk of long-term recurrence of the lesions is low, and a good clinical outcome after total or subtotal removal can be expected.
year | journal | country | edition | language |
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2016-01-01 |