6533b7d9fe1ef96bd126c3fb

RESEARCH PRODUCT

Effect of graphene and fabrication technique on the release kinetics of carvacrol from polylactic acid

Francesco LoprestiRoberto ScaffaroAndrea Maio

subject

Materials scienceKinetics02 engineering and technology010402 general chemistry01 natural sciencesEssential oillaw.inventionchemistry.chemical_compoundPolylactic acidlawControlled releaseThin filmComposite materialDuctilityElectrospinningGrapheneGeneral EngineeringSettore ING-IND/34 - Bioingegneria Industriale021001 nanoscience & nanotechnologyCastingElectrospinningSolvent casting0104 chemical sciencesSolventSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialichemistryCeramics and CompositesGraphene0210 nano-technology

description

Abstract Porous membranes and thin films containing poly-lactic acid (PLA), carvacrol (CRV) and graphene nanoplatelets (GNP) were fabricated by electrospinning and solvent casting at different formulations. The systems were characterized from a mechanical, morphological, calorimetric and spectroscopic point of view. CRV release as a function of time was studied and a mathematical model was used to fit and interpret the data in order to investigate the release mechanism. The results indicate that the incorporation of GNP generally determined a simultaneous strengthening, stiffening and toughening effect, while preserving a good ductility. Furthermore, integrating GNP allowed tuning the amount and kinetics of CRV release, and proved to reduce the initial burst release effect.

yearjournalcountryeditionlanguage
2019-01-05
10.1016/j.compscitech.2018.11.003http://hdl.handle.net/10447/369882