6533b7d9fe1ef96bd126caf1
RESEARCH PRODUCT
ChemInform Abstract: Tetramethylguanidine (TMG)-Catalyzed Addition of Dialkyl Phosphites to α,β-Unsaturated Carbonyl Compounds, Alkenenitriles, Aldehydes, Ketones and Imines.
Marinella RobertiIlaria LamprontiFrancesco Paolo InvidiataRiccardo RondaninGian Piero PolliniDaniele SimoniMonica Manferdinisubject
HydroxylationHydroborationchemistry.chemical_compoundchemistrySilylationSynthonOrganic chemistryGeneral MedicinePhosphonateCatalysisdescription
Abstract Tetramethylguanidine-catalyzed addition of dialkyl phosphites to α,β-unsaturated carbonyl compounds, alkenenitriles, aldehydes and ketones constitutes a practical route to a variety of phosphonate synthons. The very mild conditions employed, together with the short reaction times, make the procedure highly versatile and tolerant to a range of functionalities. The proposed methodology is also convenient for the preparation of α-aminophosphonates.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-06-18 | ChemInform |