6533b7d9fe1ef96bd126cbd6

RESEARCH PRODUCT

Unterschiede zwischen Tyramin und Dimethylphenylpiperazin in der Ca++-Abhängigkeit und im zeitlichen Verlauf der Noradrenalin-Freisetzung am isolierten Kaninchenherzen

K. LöffelholzErich MuschollR. Lindmar

subject

Pharmacologymedicine.medical_specialtyChemistryRabbit heartCell BiologyTyramineCellular and Molecular Neurosciencechemistry.chemical_compoundEndocrinologyInternal medicinemedicineMolecular MedicineConstant infusionMolecular Biology

description

On the perfused rabbit heart a constant infusion of tyramine released noradrenaline continuously and independently of the external Ca++ concentration. In contrast, noradrenaline release by DMPP was only transient and required the presence of Ca++.

https://doi.org/10.1007/bf02136230