6533b7d9fe1ef96bd126d601

RESEARCH PRODUCT

Klassifikation der Nierenzellkarzinome/Tumoren und ihre Beziehung zum Nephron-Sammelrohrsystem

S. StörkelW. ThoenesRumpelt Hj

subject

Cell typePathologymedicine.medical_specialtyGeneral MedicineChromophobe cellBiologyurologic and male genital diseasesmedicine.diseaseDrug DiscoveryCarcinomamedicineMolecular MedicineIntercalated CellOncocytomaGenetics (clinical)

description

After a controversial phase of nomenclature (including--among others--the terms "hypernephroma" and "hypernephroid carcinoma") a cytomorphologically defined subtyping of renal cell tumours (adenomas, carcinomas, oncocytomas) is offered, based on new electron microscopical and histochemical observations. These data are in part supported by cytogenetical findings reported in the literature. Phenotypical/histogenetical relations to different parts or cell types, respectively, of the nephron-collecting duct system could be demonstrated. Chromophobe cell carcinoma and oncocytoma exhibit features of the intercalated cells.

https://doi.org/10.1007/bf01798060