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RESEARCH PRODUCT
Bidirectional Glenn and antegrade pulmonary blood flow: temporary or definitive palliation?
David F. PetruccelliAntonio RubinoDiego GuardìKhalil FattouchDavide CalvarusoCarmelo MignosaSalvatore AgatiAdriano CiprianiCarlo MarcellettiSalvatore OcelloLucio ZanniniNicoletta Salviatosubject
Pulmonary and Respiratory MedicineAdultHeart Defects CongenitalMalemedicine.medical_specialtyPulmonary CirculationAdolescentHeart VentriclesHemodynamicsKaplan-Meier EstimateHematocritFontan ProcedureRisk AssessmentSensitivity and SpecificityPulmonary artery bandingCohort StudiesArteriovenous Shunt SurgicalInternal medicinemedicineHumansHeart bypassChildSurvival rateRetrospective StudiesLungmedicine.diagnostic_testbusiness.industryHeart Bypass RightPalliative CareInfantBlood flowSurgerySurvival Ratemedicine.anatomical_structureTreatment OutcomeChild PreschoolCirculatory systemCardiologyLinear ModelsSurgeryFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up Studiesdescription
Background We sought to investigate the role of the bidirectional Glenn with antegrade pulmonary blood flow in the surgical history of children with univentricular hearts. Methods A series of 246 patients, from three joint institutions, having univentricular heart with restricted but not critical pulmonary blood flow received a bidirectional cavopulmonary shunt with additional forward pulmonary blood flow. All patients have been studied according to their progression, or not, to Fontan operation. Two hundred and eight (84.5%) patients underwent bidirectional cavopulmonary anastomosis as primary palliation. Twenty patients (8.1%) with previous pulmonary artery banding were also enrolled in the study. Patients who had received additional pulmonary blood flow through a previous systemic to pulmonary artery shunt for the critical pulmonary blood flow were excluded. Results No in-hospital death occurred. Follow-up was complete at 100%. Mean follow-up was 4.2 ± 2.8 years (range, 6 months to 7 years). During the observational period 73 (29.7%) patients, considered optimal candidates, underwent Fontan completion for increasing cyanosis and (or) hematocrit and (or) fatigue with exertion. Three patients expired after total cavopulmonary connection (3 of 73; 4.1% mortality rate). The remaining 173 (70.3%) patients are alive with initial palliation. All patients were still well palliated with an arterial oxygen saturation at rest about 90%. Conclusions According to our experience and results, bidirectional Glenn with antegrade pulmonary blood flow may be an excellent temporary palliation prior to a Fontan operation, which can be performed at the onset of symptoms. Bidirectional Glenn may also be the best possible palliation for a suboptimal candidate for Fontan.
year | journal | country | edition | language |
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2008-04-01 | The Annals of thoracic surgery |