Histamine-sensitive adenylate cyclase of human gastric mucosa: a model for H2-receptor excitation.

6533b7d9fe1ef96bd126d7be

RESEARCH PRODUCT

Histamine-sensitive adenylate cyclase of human gastric mucosa: a model for H2-receptor excitation.

B Kommerell H Kather B Simon

subject

medicine.medical_specialty Nucleotidase activity Adenylate kinase In Vitro Techniques Cyclase chemistry.chemical_compound Histamine H2 receptor Internal medicine medicine Gastric mucosa Ethylamines Humans heterocyclic compounds Pharmacology (medical)Receptors Histamine H2 Receptors Histamine H1 Pharmacology business.industry Effector Stomach Methylhistamines digestive system diseases Stimulation Chemical medicine.anatomical_structure Endocrinology chemistry Gastric Mucosa Receptors Histamine business Histamine Research Article Adenylyl Cyclases Histamine

description

Recent studies revealed that human gastric mucosa contains a histamine-sensitive adenylate cyclase which is almost completely localized within the acid-secreting area of the stomach. In an attempt to further characterize the effector system of histamine’s action, we compared the effects of H 1 — and H 2-receptor agonists upon the adenylate cyclase in human fundic gastric mucosa.

year	journal	country	edition	language
1978-03-01

https://europepmc.org/articles/PMC1429272/

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