Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?

6533b7dafe1ef96bd126d8ae

RESEARCH PRODUCT

Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?

Víctor Collado-díaz Maria ÁNgeles Martinez-cuesta Maria ÁNgeles Martinez-cuesta Maria Amparo Blanch-ruiz Ainhoa Sánchez-lópez Patricia García-martínez José E Peris Iris Usach Maria Dolores Ivorra Alessandra Lacetera Sonsoles Martín-santamaría Juan V. Esplugues Juan V. Esplugues Juan V. Esplugues Angeles Alvarez Angeles Alvarez

subject

0301 basic medicine Agonist Allosteric modulator medicine.drug_class Allosteric modulator adenosine triphosphate Allosteric regulation Pharmacology leukocyte-endothelium interactions Proinflammatory cytokine 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine immune system diseases Abacavir medicine Pharmacology (medical)Original Research Pharmacology Apyrase Leukocyte-endothelium interactions abacavir lcsh:RM1-950 Purinergic receptor allosteric modulator virus diseases Abacavir cardiovascular diseases Cardiovascular diseases lcsh:Therapeutics. Pharmacology 030104 developmental biology chemistry P2X7 receptor Adenosine triphosphate 030217 neurology & neurosurgery Adenosine triphosphate medicine.drug

description

16 p.-9 fig.-1 tab.

year	journal	country	edition	language
2021-03-31	Frontiers in Pharmacology

https://doi.org/10.3389/fphar.2021.613449

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