6533b7dafe1ef96bd126e110

RESEARCH PRODUCT

Tanzawaic acids I-L: Four new polyketides from Penicillium sp. IBWF104-06.

Anja SchüfflerEckhard ThinesLouis P. SandjoTill Opatz

subject

biologyChemistrynatural productsOrganic Chemistrystructure elucidationfood and beveragesFungusbiology.organism_classificationFull Research PaperarohynapeneMicrobiologylcsh:QD241-441Magnaporthe oryzaeChemistrylcsh:Organic chemistryGerminationPenicilliumtanzawaic acidFungal strainlcsh:Qlcsh:Sciencepolyketides

description

Four new polyketides have been identified in culture filtrates of the fungal strain Penicillium sp. IBWF104-06 isolated from a soil sample. They are structurally based on the same trans-decalinpentanoic acid skeleton as tanzawaic acids A–H. One of the new compounds was found to inhibit the conidial germination in the rice blast fungus Magnaporthe oryzae at concentrations of 25 μg/mL.

10.3762/bjoc.10.20https://pubmed.ncbi.nlm.nih.gov/24605144