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RESEARCH PRODUCT
ChemInform Abstract: Microwave-Assisted Synthesis of Polysubstituted 4-Quinolones from Deprotonated α-Aminonitriles.
Alexandra RomekTill Opatzsubject
DeprotonationChemistry4-quinolonesGeneral MedicineMedicinal chemistryMicrowave assisteddescription
The α-alkylations of deprotonated Strecker products such as (I) or (V) give a series of intermediates such as (III), (VI), or (X), which undergo microwave-assisted HCN and EtOH eliminations leading to the title quinolones (IV), (VII)/(VIII), or (XI).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-27 | ChemInform |