6533b7dafe1ef96bd126f4e5

RESEARCH PRODUCT

Crown ethers derived from cyclohexane. Influence of their stereochemistry in complexation and transport

J. Pablo VillarroyaM. Carmen Ramírez De ArellanoSalvador GilM. José AurellAna M. Costero

subject

chemistry.chemical_compoundCyclohexanechemistryStereochemistryOrganic ChemistryDrug DiscoveryCrown (botany)Ring (chemistry)Biochemistry

description

Abstract Crown ethers derived from cyclohexane have been prepared. The trans stereochemistry of the substituents on the carbocyclic ring makes that only one conformation can complex cations. The influence of the stereochemistry in complexation has been studied.

https://doi.org/10.1016/s0040-4020(02)00681-6