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RESEARCH PRODUCT
NUTRITION, OXIDATIVE STRESS AND INTESTINAL DYSBIOSIS: INFLUENCE OF DIET ON GUT MICROBIOTA IN INFLAMMATORY BOWEL DISEASES.
Alice Gerges GeageaAlice Gerges GeageaProvvidenza DamianiMargherita MazzolaEmanuele SinagraGiovanni ZummoFrancesco CappelloAbdo JurjusTarek Bou AssiM. MessinaFrancesco CariniGiovanni TomaselloAngelo LeoneFelicia Farinasubject
0301 basic medicineSettore MED/09 - Medicina InternaPopulationhealthy dietlcsh:MedicineNutritional Statuscolorectal cancerGut floramedicine.disease_causeintestinal dysbiosisInflammatory bowel diseaseGeneral Biochemistry Genetics and Molecular BiologyMicrobiology03 medical and health sciences0302 clinical medicineIntestinal mucosaInflammatory Bowel diseases colorectal cancer intestinal dysbiosis gut microbiota MALT healthy diet.medicineOily fishHumanseducationeducation.field_of_studybiologygut microbiotabusiness.industrylcsh:RPathogenic bacteriamedicine.diseasebiology.organism_classificationInflammatory Bowel DiseasesUlcerative colitisDietGastrointestinal MicrobiomeOxidative StressSettore MED/18 - Chirurgia Generale030104 developmental biology030220 oncology & carcinogenesisImmunologyDysbiosisbusinessDysbiosisdescription
Background: Microbiota refers to the population of microorganisms (bacteria, viruses and fungi) that inhabit the entire gastrointestinal tract, more particularly the colon whose role is to maintain the integrity of the intestinal mucosa and control the proliferation of pathogenic bacteria. Alteration in the composition of the gut microbiota is called dysbiosis. Dysbiosis redisposes to inflammatory bowel diseases such as ulcerative colitis, Crohn disease and indeterminate colitis. Methods: The purpose of this literature review is to elucidate the influence of diet on the composition of the gastrointestinal microbiota in the healthy gut and the role of diet in the development of dysbiosis. Conclusion: The "Western diet", in particular a low - fiber high fat/high carbohydrate diet is one factor that can lead to severe dysbiosis. In contrast, "mediterranean" and vegetarian diets that includes abundant fruits, vegetables, olive oil and oily fish are known for their anti-inflammatory effects and could prevent dysbiosis and subsequent inflammatory bowel disease.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-12-01 |