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RESEARCH PRODUCT
Hypovitaminosis D and fat mass in healthy older people
Alessandra CoinGiuseppe SergiCaterina TrevisanS. CarraroS SartiM. De RuiBruno Micael ZanforliniNicola VeroneseEnzo ManzatoEnzo Manzatosubject
MaleVitaminmedicine.medical_specialtyCalorieCross-sectional studyAbdominal FatMedicine (miscellaneous)030209 endocrinology & metabolismLogistic regressionBody Mass IndexNO03 medical and health scienceschemistry.chemical_compoundAbsorptiometry Photon0302 clinical medicineInternal medicineVitamin D and neurologyHumansMedicineProspective Studies030212 general & internal medicineVitamin DProspective cohort studyNutrition and Dieteticsbusiness.industryMiddle AgedVitamin D Deficiencymedicine.diseaseObesityMedicine (miscellaneous); Nutrition and DieteticsCross-Sectional StudiesEndocrinologychemistryObesity AbdominalBody CompositionFemalebusinessBody mass indexFollow-Up Studiesdescription
Prospective studies have suggested that hypovitaminosis D can predict the onset of obesity, but they relied mainly on body mass index, which could be scarcely reliable in older people. We investigated whether baseline hypovitaminosis D could predict higher fat mass (FM) levels using dual-energy X-ray absorptiometry in a sample of 116 fit and healthy older subjects. Although no significant differences in FM estimates emerged between subjects with and without hypovitaminosis D at the baseline, abdominal FM was found significantly higher in the former group (with hypovitaminosis D at the baseline) than in the latter after 3 years of follow-up. Adjusted logistic regression analysis confirmed these findings: hypovitaminosis D coincided with an approximately sixfold higher risk of subjects having higher abdominal FM levels at the follow-up. In conclusion, hypovitaminosis D predicts higher abdominal FM levels in the elderly. © 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 |