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RESEARCH PRODUCT
Boric acid toxicity to the German cockroach, Blattella germanica: Alterations in midgut structure, and acetylcholinesterase and glutathione S-transferase activity
Jean-pierre FarineNadia AribiNoureddine SoltaniSamira MorakchiDahbia Habessubject
0106 biological sciencesAchéHealth Toxicology and MutagenesisBiology01 natural sciences03 medical and health scienceschemistry.chemical_compoundMidgutPesticides030304 developmental biology2. Zero hunger0303 health sciencesGerman cockroachDictyopteraMidgutGeneral MedicineGlutathionebiology.organism_classificationBoric acidAcetylcholinesteraselanguage.human_language3. Good healthGlutathione S-transferase010602 entomologyGlutathione S-transferaseBlattella germanicachemistryBiochemistryToxicitylanguagebiology.proteinAcetylcholinesteraseAgronomy and Crop Sciencedescription
0048-3575 doi: DOI: 10.1016/j.pestbp.2005.05.002; Oral toxicity of boric acid, an inorganic insecticide, was evaluated on German cockroach, Blattella germanica L. (Dictyoptera, Blattellidae). Newly emerged adults were exposed to various concentrations of boric acid incorporated into the diet. Results showed that treated insects exhibited toxic symptoms with a dose-dependent mortality. Histological study of midgut revealed alterations in the epithelial cells and a signiWcant increase in the epithelium thickness. In a second series of experiments, the compound was investigated on the activities of acetylcholinesterase (AChE) and glutathione S-transferases (GSTs). Data showed that the compound induced GSTs and reduced the activity of AChE. From this experiment, it may be concluded that ingested boric acid caused death of insects perhaps ultimately by starvation via alterations of the midgut. Additionally, the compound seemed to present a neurotoxic action as evidenced by the symptoms of poisoning and the reduction in AchE activity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-01-01 |