6533b7dafe1ef96bd126f63d

RESEARCH PRODUCT

Gypsy endogenous retrovirus maintains potential infectivity in several species of Drosophilids.

José Vicente LlorensIsabel Martinez-garayM. J. Martínez-sebastiánRosa De FrutosSirena SorianoJonathan B. Clark

subject

RetroelementsEvolutionvirusesGenome InsectEndogenous retrovirusSequence alignmentGenes InsectGenes envEvolution MolecularOpen Reading FramesViral Envelope ProteinsPhylogeneticsDrosophilidaeQH359-425AnimalsDrosophilidaeRNA MessengerDrosophila (subgenus)Cloning MolecularGeneEcology Evolution Behavior and SystematicsPhylogenyGeneticsLikelihood FunctionsbiologyModels GeneticReverse Transcriptase Polymerase Chain ReactionEndogenous RetrovirusesDNASequence Analysis DNAbiology.organism_classificationOpen reading frameProtein BiosynthesisDrosophila melanogasterSequence AlignmentResearch Article

description

Abstract Background Sequences homologous to the gypsy retroelement from Drosophila melanogaster are widely distributed among drosophilids. The structure of gypsy includes an open reading frame resembling the retroviral gene env, which is responsible for the infectious properties of retroviruses. Results In this study we report molecular and phylogeny analysis of the complete env gene from ten species of the obscura group of the genus Drosophila and one species from the genus Scaptomyza. Conclusion The results indicate that in most cases env sequences could produce a functional Env protein and therefore maintain the infectious capability of gypsy in these species.

yearjournalcountryeditionlanguage
2008-10-31BMC evolutionary biology
10.1186/1471-2148-8-302https://pubmed.ncbi.nlm.nih.gov/18976468