6533b7dbfe1ef96bd126f85f

RESEARCH PRODUCT

Lead Excretion in Spanish Children with Autism Spectrum Disorder

Carmen Puig-alcarazOmar CauliMilagros Fuentes-albero

subject

leadPediatricsmedicine.medical_specialtyGeneral NeuroscienceConfoundingDMS IVautism spectrum disorderUrinecore symptomsmedicine.diseaseArticlelcsh:RC321-571ExcretionAutism spectrum disordermental disordersmedicinebiomarkerStatistical analysisCore symptomsLead (electronics)Psychologylcsh:Neurosciences. Biological psychiatry. NeuropsychiatryClinical evaluation

description

Among epigenetic factors leading to increased prevalence of juvenile neuropsychiatric disorders, including autism spectrum disorder, exposure to metals, such as lead (Pb) have led to conflicting results. The aim of the present study was to determine the levels of Pb in the urine of children with autism spectrum disorder (ASD) compared with typically developing children (TD) age- and sex-matched, and to analyze any association between core symptoms of ASD, special diets, supplements intake or prescription drugs and the concentration of Pb. The study was performed in a group of children with ASD (n = 35, average age 7.4 ± 0.5 years) and TD (n = 34, average age 7.7 ± 0.9 years). Measurement of lead in urine was performed by atomic absorption spectrometry

yearjournalcountryeditionlanguage
2015-02-16Brain Sciences
https://doi.org/10.3390/brainsci5010058