6533b7dbfe1ef96bd126fe13

RESEARCH PRODUCT

Network of Cells and Mediators of Innate and Adaptive Cutaneous Immunity

Esther Von Stebut

subject

Innate immune systemintegumentary systemanimal diseaseschemical and pharmacologic phenomenabiochemical phenomena metabolism and nutritionBiologyCutaneous immunityAcquired immune systemImmune systemImmunityImmunologybacteriaSkin immunityArthropod Vector

description

The skin is a major surface organ that translates external signals from the environment into local and systemic immune responses. As such, it is also strongly involved in fighting against cutaneous pathogens transmitted by arthropod vectors to the host. By harboring various skin-resident as well as highly motile immune cells and unique molecules, the skin orchestrates resulting immune responses against pathogens. Only an understanding of the complexity of skin immunity will lead to a better assessment of vector-induced alterations of resulting antipathogen immunity.

https://doi.org/10.1016/b978-0-12-805360-7.00001-0