6533b7dbfe1ef96bd126fffc

RESEARCH PRODUCT

Mixtures of lecithin with polymerizable derivatives of cholesterol. A monolayer film balance study.

O. AlbrechtWerner PrassHelmut Ringsdorf

subject

food.ingredient12-DipalmitoylphosphatidylcholinePolymersUltraviolet RaysBiophysicsMembrane biologyLecithinchemistry.chemical_compoundMembrane LipidsfoodMonolayerPhase diagramCholesterolBalance studyViscositytechnology industry and agricultureWaterGeneral MedicineCholesterolchemistryChemical engineeringPolymerizationModels ChemicalThermodynamicslipids (amino acids peptides and proteins)Cholesterol Esters

description

One of the best investigated binary lipid mixtures is the lecithin-cholesterol system. We show here that it is possible to modify the cholesterol in such a way that it can be polymerized without changing its behaviour in mixtures with lecithin. The polymerizable derivatives exhibit a very similar phase diagram in the mixture with dipalmitoyl-phosphatidylcholine as the cholesterol itself. This is demonstrated by filmbalance measurements.

10.1007/bf00263066https://pubmed.ncbi.nlm.nih.gov/3816704