6533b7dbfe1ef96bd1270112

RESEARCH PRODUCT

Self-assembly of small gold colloids with functionalized gold nanorods.

Inga ZinsSebastien PierratCarsten SönnichsenAnd Aaron Breivogel

subject

chemistry.chemical_classificationNanostructureMaterials scienceMechanical EngineeringBiomoleculeNanoparticleBioengineeringNanotechnologyGeneral ChemistryPolyethylene glycolCondensed Matter Physicschemistry.chemical_compoundchemistryTransmission electron microscopyGeneral Materials ScienceNanorodSelf-assemblyBifunctional

description

We present a general strategy to stabilize gold nanorod suspensions with mono- and bifunctional polyethylene glycol (PEG) and to attach a controlled number of nanoparticles or biomolecules. Characterization by gel electrophoresis, transmission electron microscopy (TEM), and optical dark-field microscopy show the specific binding of functionalized nanorods to their target while avoiding nonspecific binding to substrates, matrices, and other particles. Such nanorods are well suited for self-assembly of nanostructures and single-molecule labeling.

10.1021/nl062131phttps://pubmed.ncbi.nlm.nih.gov/17297987