6533b7dbfe1ef96bd1270943
RESEARCH PRODUCT
Solid-phase synthesis of a glycopeptide from the homophilic recognition domain of epithelial cadherin 1 using a O-pentafluorophenyluronium salt
Jörg HabermannHorst Kunzsubject
Allylic rearrangementCadherinStereochemistryOrganic ChemistryBiochemistryGlycopeptidechemistry.chemical_compoundSolid-phase synthesischemistryAntigenPhase (matter)HexafluorophosphateDrug DiscoverySide chaindescription
Abstract The β-turn forming glycopeptide 6 from the homophilic recognition domain of mouse epithelial cadherin 1 carrying a T N -antigen side chain was synthesised on solid phase using an allylic anchor and the new coupling reagent N , N - N ′, N ′-bis(tetramethylene)- O -pentafluorophenyluronium hexafluorophosphate 3 .
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1998-01-01 | Tetrahedron Letters |