0000000000000288

AUTHOR

Jörg Habermann

showing 7 related works from this author

Chemistry of glycopeptides

1999

For a long time, peptides and proteins on the one hand and carbohydrates on the other have been considered separate classes of natural products. The rather strict distinction between these major fields of natural product chemistry is still apparent not only in the organisation of chemistry text books but also in the different approaches to immunological and cell biological recognition phenomena.

chemistry.chemical_compoundNatural productChemistryOrganic chemistryChemistry (relationship)Natural (archaeology)
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Solid-phase synthesis of a glycopeptide from the homophilic recognition domain of epithelial cadherin 1 using a O-pentafluorophenyluronium salt

1998

Abstract The β-turn forming glycopeptide 6 from the homophilic recognition domain of mouse epithelial cadherin 1 carrying a T N -antigen side chain was synthesised on solid phase using an allylic anchor and the new coupling reagent N , N - N ′, N ′-bis(tetramethylene)- O -pentafluorophenyluronium hexafluorophosphate 3 .

Allylic rearrangementCadherinStereochemistryOrganic ChemistryBiochemistryGlycopeptidechemistry.chemical_compoundSolid-phase synthesischemistryAntigenPhase (matter)HexafluorophosphateDrug DiscoverySide chainTetrahedron Letters
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Fragment condensation on solid-phase in the synthesis of an amphiphilic glycopeptide from the homophilic recognition domain of epithelial cadherin 1

1998

Abstract The lipo-glycopeptide 6 containing the homophilic recognition motif of mouse epithelial cadherin 1 was synthesised via a fragment condensation on a solid phase linked peptide using an allylic anchor and a pentafluorophenol-based coupling reagent.

chemistry.chemical_classificationAllylic rearrangementFragment (computer graphics)CadherinStereochemistryOrganic ChemistryCondensationPeptideBiochemistryGlycopeptidechemistryPhase (matter)Drug DiscoveryAmphiphileTetrahedron Letters
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Induction of Cell Differentiation in Transformed Keratinocytes by Synthetic (Glyco)peptides from the Homophilic Recognition Domain of E-Cadherin

2002

KeratinocytesProtein ConformationCadherinChemistryStereochemistryCellular differentiationMolecular Sequence DataGlycopeptidesCell DifferentiationGeneral ChemistryCadherinsPeptide FragmentsCatalysisGlycopeptideProtein Structure TertiaryDomain (software engineering)Cell biologySolid-phase synthesisMicroscopy FluorescenceHumansAmino Acid SequenceNuclear Magnetic Resonance BiomolecularCell Line TransformedAngewandte Chemie International Edition
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ChemInform Abstract: Glycopeptide Synthesis Using O-Pentafluorophenyluronium Salts as Novel Condensing Reagents.

2010

Pentafluorophenyluronium salts and related coupling reagents for the solid-phase synthesis of peptides and glycopeptides have been developed and employed in the synthesis of a glycopeptide sequence from the cell adhesion molecule E-CAD 1.

chemistry.chemical_classificationchemistryCell adhesion moleculeReagentSequence (biology)General MedicineCombinatorial chemistryGlycopeptideAmino acidChemInform
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Synthetische (Glyco)peptide aus der homophilen Erkennungsregion von E-Cadherin zur Induktion von Zelldifferenzierung in transformierten Keratinocyten

2002

CadherinChemistryGeneral MedicineMolecular biologyGlycopeptideAngewandte Chemie
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ChemInform Abstract: Glycoconjugates as Tumor-Associated Antigens and Ligands in Regulatory Processes

2010

chemistry.chemical_classificationchemistryBiochemistryGlycoconjugateStereochemistryGeneral MedicineTumor associated antigenChemInform
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