6533b822fe1ef96bd127d5e3
RESEARCH PRODUCT
Fragment condensation on solid-phase in the synthesis of an amphiphilic glycopeptide from the homophilic recognition domain of epithelial cadherin 1
Horst KunzJörg Habermannsubject
chemistry.chemical_classificationAllylic rearrangementFragment (computer graphics)CadherinStereochemistryOrganic ChemistryCondensationPeptideBiochemistryGlycopeptidechemistryPhase (matter)Drug DiscoveryAmphiphiledescription
Abstract The lipo-glycopeptide 6 containing the homophilic recognition motif of mouse epithelial cadherin 1 was synthesised via a fragment condensation on a solid phase linked peptide using an allylic anchor and a pentafluorophenol-based coupling reagent.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1998-07-01 | Tetrahedron Letters |