6533b7dbfe1ef96bd1270a6c

RESEARCH PRODUCT

Drimane Sesquiterpenoids from Marasmius sp. Inhibiting the Conidial Germination of Plant-Pathogenic Fungi

Johannes C. LiermannHeidrun AnkeTill OpatzEckhard Thines

subject

Polycyclic SesquiterpenesPharmacologyAntifungal AgentsMolecular StructureStrain (chemistry)BasidiomycotaOrganic ChemistryPharmaceutical ScienceSpores FungalBiologybiology.organism_classificationMarasmiusMarasmiusAnalytical ChemistryComplementary and alternative medicineGerminationDrug DiscoveryBotanyMolecular MedicineMarasmene BMarasmius sp.SesquiterpenesInhibitory effectBiological evaluation

description

From the basidiomycete Marasmius sp., strain IBWF 96046, three new sesquiterpenoids based on the drimane skeleton were isolated and named marasmene B and marasmals B and C. In this study, their isolation, structure elucidation, and biological evaluation are described. The compounds have a pronounced inhibitory effect on the conidial germination of several plant-pathogenic fungi.

https://doi.org/10.1021/np300337w