6533b7dbfe1ef96bd1270aee
RESEARCH PRODUCT
N-(tert-butoxycarbonylglycyl-alpha,beta-dehydrophenylalanylglycylphenylalanyl)-4-nitroaniline.
Krzysztof EjsmontJacek ZaleskiMaciej Makowskisubject
chemistry.chemical_classificationTetrapeptideHydrogen bondStereochemistryPeptideGeneral MedicineCrystal structureGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundAnilinechemistryIntramolecular forceNitroMoleculedescription
In the crystal structure of the tetrapeptide Boc0–Gly1–ΔPhe2–Gly3–Phe4–p-NA (p-NA is para-nitroaniline), C33H36N6O8, there are two independent molecules differing in conformation in the asymmetric part of the unit cell. All the amino acids in the peptide are linked trans to each other. The torsion angles in the main chain of both molecules are close to the values of the type β-II turn. Two intramolecular and three intermolecular N—H⋯O hydrogen bonds stabilize the conformation of each of the molecules.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-09-27 | Acta crystallographica. Section C, Crystal structure communications |