Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases

6533b7dbfe1ef96bd1270b2a

RESEARCH PRODUCT

Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases

Claudia Pielsticker Kerstin Jurk Kerstin Jurk Lisa Raum Martin Brodde Beate E. Kehrel

subject

0301 basic medicine Protein Folding Platelet Aggregation Plasmin 030204 cardiovascular system & hematology Protein aggregation Fibrinogen Thrombospondin 1 0302 clinical medicine Platelet Fibrinolysin protein misfolding Isomerases Spectroscopy Chemistry food and beverages General Medicine thiol-isomerases Computer Science Applications Cell biology P-Selectin platelets medicine.drug circulatory and respiratory physiology Blood Platelets Catalysis Article Inorganic Chemistry 03 medical and health sciences Protein Aggregates Thrombospondin 1 medicine Humans Platelet activation Sulfhydryl Compounds Physical and Theoretical Chemistry thrombospondin-1 Molecular Biology plasmin Inflammation Organic Chemistry fungi Fibrinogen binding Fibrinogen Plasminogen Platelet Activation 030104 developmental biology Protein Conformation beta-Strand Peptides Plasminogen activator

description

Inflammatory processes are triggered by the fibrinolytic enzyme plasmin. Tissue-type plasminogen activator, which cleaves plasminogen to plasmin, can be activated by the cross-&beta

year	journal	country	edition	language
2020-11-23	International Journal of Molecular Sciences

10.3390/ijms21228851 http://dx.doi.org/10.3390/ijms21228851

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