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RESEARCH PRODUCT
Effect of probe contact pressure on the photoplethysmographic assessment of conduit artery stiffness
Edgars Kviesis-kipgeAndris GrabovskisZbignevs MarcinkevicsUldis Rubinssubject
AdultMalemedicine.medical_specialtyMaterials scienceOptical PhenomenaCoefficient of variationBiomedical EngineeringBlood PressureDerivativePulse Wave AnalysisSignalBiomaterialsYoung AdultVascular StiffnessPhotoplethysmogramPressuremedicineHumansPulse wavePhotoplethysmographyBlood VolumePulse (signal processing)Optical DevicesRepeatabilityAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsSurgeryTransducerFemaleBiomedical engineeringdescription
Currently, photoplethysmography (PPG) is a frequently studied optical blood pulsation detection tech- nique among biophotonic and biomedical researchers due to the fact that it shows high potential for estimating the arterial stiffness (AS). The extraction of diagnostically useful information requires standardized measurement pro- cedure with good repeatability. However, the effects of a crucially important factor—the optimal contact pressure (CP) of the probe—are often ignored. Also, CP values are not reported to evaluate those effects. It is hypothesized that AS estimated from PPG pulse wave 2nd derivative parameter b∕a is strongly inconsistent when recorded at nonoptimal probe CP. Our pilot study confirmed this during in vivo PPG recordings from conduit artery sites on five healthy subjects at variable probe CP (0 to 15 kPa) by using 880 nm reflectance type sensor, force transducer, and PPG alternating current (AC) signal pulse area derived optimal CP criterion. The b∕a values, calculated from PPG with variable CP, showed variation >300 percent. In contrast, at the optimal CP, the b∕a showed high repeatability (coefficient of variability <5 percent). The effect has been explained with exponential pulse pressure-volume rela- tionship model which indicates the optimal CP range.©2013 Society ofPhoto-OpticalInstrumentation Engineers (SPIE)(DOI:10.1117/1
year | journal | country | edition | language |
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2013-02-01 | Journal of Biomedical Optics |