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RESEARCH PRODUCT

Gelation behavior of 5-chloro-8-hydroxyquinoline, an antituberculosis agent, in aqueous alcohol solutions

Jukka KorpelaErkki KolehmainenHannu Salo

subject

Microbiology (medical)gelScanning electron microscope5-kloori-8-hydroksikinoliinigel; 5-chloro-8-hydroxyquinoline; <em>Mycobacterium </em><em>tuberculosis</em>gelationBiochemistryMicrobiologyArticle5-chloro-8-hydroxyquinolinechemistry.chemical_compoundOrganic chemistryPharmacology (medical)Thermal stabilityGeneral Pharmacology Toxicology and Pharmaceuticsta116Aqueous alcoholgeelin muodostusTransition temperature5-chloro-8-hydoxyquinolinelcsh:RM1-950Antituberculosis agent8-HydroxyquinolineMycobacterium tuberculosisInfectious Diseaseslcsh:Therapeutics. PharmacologychemistryNuclear chemistry

description

It was shown that 5-chloro-8-hydroxyquinoline, an antituberculosis agent, gels aqueous alcohol solutions efficiently. Thermal stability and gel-to-sol transition temperature of 1% gel in CD3OD/D2O (2:1) was studied by 1H-NMR. Fibrous structures of four xerogels have been characterized by scanning electron microscope. peerReviewed

yearjournalcountryeditionlanguage
2012-09-19Antibiotics
10.3390/antibiotics1010017https://doi.org/10.3390/antibiotics1010017