6533b7dbfe1ef96bd1270c76

RESEARCH PRODUCT

Sensitivity of alanine dosimeters with gadolinium exposed to 6 MV photons at clinical doses.

Maurizio MarraleAnna LongoMaria BraiAntonio BartolottaMaria Cristina D'ocaM. Spanò

subject

PhotonESR dosimetryGadoliniumMonte Carlo methodAccelerationBiophysicschemistry.chemical_elementGadoliniumLinear particle acceleratorRadiology Nuclear Medicine and imagingIrradiationRadiometryMonte Carlo simulationAlaninePhotonsRadiationDosimeterAlanineChemistryX-RaysRadiochemistryElectron Spin Resonance SpectroscopyDose-Response Relationship RadiationSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Alanine dosimeters gadoliniumLinear ModelsSensitivity (electronics)Monte Carlo Method

description

In this study we analyzed the ESR signal of alanine dosimeters with gadolinium exposed to 6 MV linear accelerator photons. We observed that the addition of gadolinium brings about an improvement in the sensitivity to photons because of its high atomic number. The experimental data indicated that the addition of gadolinium increases the sensitivity of the alanine to 6 MV photons. This enhancement was better observed at high gadolinium concentrations for which the tissue equivalence is heavily reduced. However, information about the irradiation setup and of the radiation beam features allows one to correct for this difference. Monte Carlo simulations were carried out to obtain information on the expected effect of the addition of gadolinium on the dose absorbed by the alanine molecules inside the pellets. These results are compared with the experimental values, and the agreement is discussed.

10.1667/rr2256.1https://pubmed.ncbi.nlm.nih.gov/21823974